Moreover, the occurrence of four deaths in the febuxostat groups, as compared with none in the allopurinol group, is further reason for pause.

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Th occunc hypsnsitivity actions tZYLOPIM (allopuinol) may b incasd in patints with dcasd nal unction civing thiazids and ZYLOPIM (allopuinol) concuntly. this ason, in this clinical stting, such combinations should b administd with caution and patints should b obsvd closly.

Hypuicmia may b pimay, as in gout, sconday tdisass such as acut and chonic lukmia, polycythmia va, multipl myloma, and psoiasis. It may occu with th us diutic agnts, duing nal dialysis, in th psnc nal damag, duing stavation ducing dits, and in th tatmnt noplastic disas wh apid solution tissu masss may occu. Asymptomatic hypuicmia is not an indication tatmnt with ZYLOPIM (s INDICATIONS ).

Dnot stAllopuinol Sandoz any oth mdicin in th bathoom na a sink. Dnot lav it on a window sill in th ca.

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as with allopurinol, febuxostat should not be combined with azathioprine imuran , mercaptopurine, or theophylline; these medications can reach toxic levels in the blood because xanthine oxidase is partially responsible for their metabolism.