In a study examining ethionamide resistance, ethionamide administered orally initially decreased the number of culturable i mycobacterium tuberculosis i organisms from the lungs of h37rv infected mice.

Information about Ethionamide.
UsesTreatment of active tuberculosis in patients with Mycobacterium tuberculosis resistant to isoniazid or rifampinTreatment of active tuberculosis in patients infected with M tuberculosis when there is intolerance to other drugs.
If you have diabetescheck your blood sugar carefully while taking ethionamide.
Signs of an allergic reactionlike rashhivesitchingredswollenblisteredor peeling skin with or without feverwheezingtightness in the chest or throattrouble breathingswallowingor talkingunusual hoarsenessor swelling of the mouthfacelipstongueor throatSigns of liver problems like dark urinefeeling tirednot hungryupset stomach or stomach painlight-colored stoolsthrowing upor yellow skin or eyesSigns of low thyroid levels like hard stoolsconstipationnot able to handle coldmemory problemsmood changesor a burningnumbnessor tingling feeling that is not normalLump on your neckLow mooddepressionMentalmoodor behavior changes that are new or worseChange in eyesighteye painor very bad eye irritationLoss of eyesightVery bad dizziness or passing outLow blood sugar may occurSigns may be dizzinessheadachefeeling sleepyfeeling weakshakinga fast heartbeatconfusionhungeror sweatingCall the doctor right away if any of these signs occurFollow what you have been told to do if low blood sugar occursThis may include taking glucose tabletsliquid glucoseor some fruit juices.
Tell your doctor right away if any of these unlikely but serious side effects occurunusual hungerunusual sweatingshakinesspersistent nausea/vomitingunusual tiredness/weaknessyellowing eyes/skindark urinejoint pain/swellingslow heartbeatmental/mood changessuch as nervousnessrestlessnessdepression
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figure 79 2012-2017 global ethionamide consumption volume market share by application.