Short-term less than or equal to 4 days coadministration of aspirin with pletal increased the inhibition of arachidonic acid-induced ex vivo platelet aggregation by 20 compared to pletal alone and by 48 compared to aspirin alone.
Information about Pletal.
Caution should be exercised when co-administering cilostazol with any other agents that inhibit platelet aggregationRefer to sections 4.3 and 4.5
Patients may respond as early as 2 to 4 weeks after the initiation of therapybut treatment for up to 12 weeks may be needed before a beneficial effect is experiencedIf symptoms are unimproved after 3 monthsdiscontinue PLETAL.
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leafletDo not use Pletal for a condition for which it was not prescribedDo not give Pletal to other peopleeven if they have the same symptoms that you haveIt may harm them.
Medications similar to cilostazol have caused seriouspossibly fatalproblems in people with a certain type of heart diseaseheart failureThereforedo not use cilostazol if you have heart failure.
Figure 2 depicts the percent mean improvement in maximal walking distanceat study end for each of the eight studies.
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