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The PBAC noted that ivermectin is currently PBS subsidised for the treatment of onchocerciasis and stronglyloidiasisThe PBAC had not previously considered a submission for ivermectin for the treatment of scabies.

Vision changes or problems with your visionurinary or bowel problemsweaknessconfusionlack of coordinationeye rednessswellingor painor seizureconvulsions

Drugs that inhibit P-glycoprotein include verapamiltrifluoperazinecyclosporinetamoxifenvincristineclarithromycinerythromycinand omeprazole.

Clinical reportsnon-randomisedof ivermectin for the treatment of crusted scabiesfrom Section C of the submissionAnalysis of 5 direct trials comparing ivermectin and benzyl benzoate for the treatment of typical scabiesfrom the Cochrane ReviewStrong and JohnstoneInterventions for treating scabies

Many drugs inhibit CYP3A4including statinsHIV protease inhibitorsdexamethasonelidocainebarbituratessuch as phenobarbitalbutalbitalbenzodiazepinessuch as clonazepamlorazepamand valproic acid.

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