Zestoretic contains a combination of 2 drugs, lisinopril and hydrochlorothiazide .

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Dizzinesslightheadednesstirednessor headache may occur as your body adjusts to the medicationDry cough may also occurIf any of these effects last or get worsetell your doctor or pharmacist promptly.

Take Zestoretic exactly as prescribed by your doctorFollow all directions on your prescription labelYour doctor may occasionally change your doseDo not take this medicine in larger or smaller amounts or for longer than recommended.

Hydrochlorothiazide is excreted in human milk in small amountsThiazides in high doses causing intense diuresis can inhibit the milk productionThe use of lisinopril/hydrochlorothiazide during breast feeding is not recommendedIf lisinopril/hydrochlorothiazide is used during breast feedingdoses should be kept as low as possible.

Elevations in serum potassium have been observed in some patients treated with ACE inhibitorsincluding lisinoprilPatients at risk for the development of hyperkalaemia include those with renal insufficiencydiabetes mellitusor those using concomitant potassium-sparing diureticspotassium supplements or potassium-containing salt substitutesor those patients taking other drugs associated with increases in serum potassiume.gheparinthe combination trimethoprim/sulfamethoxazole also known as co-trimoxazoleIf concomitant use of the above-mentioned agents is deemed appropriateregular monitoring of serum potassium is recommendedsee section 4.5

If you need surgery or medical teststell the doctor ahead of time that you are taking medicine that contains hydrochlorothiazide.

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