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You should not use Prograf if you are allergic to tacrolimus or hydrogenated castor oilor if you have used cyclosporineNeoralSandimmuneGengrafwithin the past 24 hours.
Before you take PROGRAFtell your healthcare provider about all of your medical conditionsincluding if youplan to receive any live vaccinespeople taking PROGRAF should not receive live vaccineshave or have had liverkidney or heart problems are pregnant or plan to become pregnantPROGRAF can harm your unborn babyIf you are able to become pregnantyou should use effective birth control before and during treatment with PROGRAFTalk to your healthcare provider before starting treatment with PROGRAF about birth control methods that may be right for youMales who have female partners who are able to become pregnant should also use effective birth control before and during treatment with PROGRAFTalk to your healthcare provider before starting treatment with PROGRAF about birth control methods that may be right for youare breastfeeding or plan to breastfeedPROGRAF passes into your breast milkYou and your healthcare provider should decide if you will breastfeed while taking PROGRAF.
The data in kidney transplant patients indicate that the Black patients required a higher dose to attain comparable trough concentrations compared to Caucasian patientsTable 2
Prograf should not be used simultaneously with cyclosporinePrograf or cyclosporine should be discontinued at least 24 hours before initiating the otherIn the presence of elevated Prograf or cyclosporine concentrationsdosing with the other drug usually should be further delayed.
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