Nsaids, including ponstel, should be used with caution in patients with hypertension.
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Elevations of ALT or ASTthree or more times the upper limit of normalULNhave been reported in approximately 1of NSAID-treated patients in clinical trialsIn additionraresometimes fatalcases of severe hepatic injuryincluding fulminant hepatitisliver necrosisand hepatic failure have been reported.
Inform patients not to use low-dose aspirin concomitantly with Ponstel until they talk to their healthcare providersee PRECAUTIONSDrug Interactions
Do not drink alcohol while taking mefenamic acidAlcohol can increase the risk of stomach bleeding.
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