Your risk of easy bruising or bleeding increases if you take certain antidepressants such as duloxetine, escitalopram, duloxetine, fluvoxamine, sertraline, fluoxetine, or venlafaxine along with indocin.

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SSRIs work by restoring the balance of a brain neurotransmitter called serotonin by blocking its entry back into the nerve cells.

Do not use concurrently with alosetronastemizolecisapridepimozideterfenadineor tizanidine due to QT prolongation risk.

Syndrome of inapropriate antidiuretic hormone and hyponatremia reported with SSRI and SNRI usevolume deplretion and/or concurrent use of diuretics may increase riskconsider discontinuing therapy if symptomatic hyponatremia occurs.

Antidepressant medications are used to treat a variety of conditionsincluding depression and other mental/mood disordersThese medications can help prevent suicidal thoughts/attempts and provide other important benefitsHoweverstudies have shown that a small number of peopleespecially people younger than 25who take antidepressants for any condition may experience worsening depressionother mental/mood symptomsor suicidal thoughts/attemptsThereforeit is very important to talk with the doctor about the risks and benefits of antidepressant medicationespecially for people younger than 25even if treatment is not for a mental/mood condition.

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